![]() In a double-blind, randomized trial, 80 overweight adults were given chromium picolinate (1000 mcg/day) or placebo and followed a nutritional regimen for 24 weeks. The researchers concluded that “ Twelve weeks of 400 microg/day of chromium as a CP supplement did not significantly affect body composition, RMR…” 8Ĭhromium picolinate (1000 mcg) does not appear to promote weight loss in overweight adults.Neither body composition nor resting metabolic rate was significantly changed by chromium picolinate supplementation. Forty-four women were assigned to take placebo or CrPic 400 mcg/day along with the exercise program. This randomized, double-blind study looked at the effects of chromium picolinate on body composition in obese women undergoing 12 weeks of exercise. Meanwhile, the few successful studies are largely restricted to people with eating disorders, depression or diabetes.Ĭhromium picolinate (400 mcg) does not appear to promote weight loss in obese women undergoing exercise The majority of studies on chromium picolinate supplementation show that it does not have a significant impact on body weight. In 1997, the US Federal Trade Commission (FTC) ordered entities associated with CrPic manufacturing and distribution to stop making claims of body fat reduction, weight loss, and muscle mass increases. Meanwhile, the large majority of studies in healthy overweight or obese individuals show a lack of effect on body composition. ![]() And even in these cases, the weight loss effect seems to be relatively minor. But although it has been suggested to reduce appetite and food intake - resulting in weight loss - it’s important to highlight that this effect seems to be restricted to people with specific conditions, namely diabetes, eating disorders, and depression. 5 Chromium Picolinate’s Fat Burning BenefitsĬhromium picolinate is a popular supplement for controlling food cravings. However, this biological activity is yet to be fully understood and has only been demonstrated in rats. ![]() Another possibility is that it may do this by enhancing insulin-sensitive systems in the brain. 4 Affecting brain neurotransmittersĬrPic may be able to reduce hunger and subsequent food intake by affecting the levels of several brain neurotransmitters involved in the regulation of appetite and food cravings, such as serotonin. Through this action, it is believed to improve insulin sensitivity and blood glucose levels, the central characteristics of diabetes. Low-molecular-weight chromium-binding substance (also known as chromodulin) is a molecule that transports chromium in the body and interacts with the insulin receptor. Chromodulin’s interaction with the insulin receptor However, researchers have suggested several possibilities. The precise molecular mechanism of chromium picolinate on metabolism and body composition remains unclear. By Sbharris, via Wikimedia Commons How Chromium Picolinate Might Help Weight Loss The refining of grains and sugars and the processing of food removes most of the absorbable chromium, reducing the amount we get through diet.
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